IRB Review Process
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Last Updated: Mar 26, 2026, 04:23 PM
IRB Review Process
The information below outlines the IRB process for submissions, review, and modifications. As always, if you have any questions don't hesitate to contact us.
Submission
Submit the completed IRB application to siuhsc@siu.edu. Attach any supplementary materials, such as consent forms, recruitment documents, survey questions, and permission letters.
Before submitting your IRB application, be sure to sign it! All IRB applications require an official signature. If you're a student researcher, both your signature and your faculty advisor's signature are required.
Review
The IRB administrative office coordinates with the Institutional Review Board to complete the review process.
If the protocol is determined to require Full Board Review, the IRB will review the application during a convened meeting. The IRB meets on the second Friday of the month. All other submissions are reviewed by the IRB Chair and/or a designated IRB reviewer.
After a protocol is reviewed, either by the full board or designated review, the PI may receive a revision request. Revision requests may occur more than once before approval. Responding to revision requests in a timely manner ensures that the protocol is reviewed with minimal delays.
Approval
When protocols are approved, a formal memo is generated to the PI. Research cannot begin until you receive your official approval letter from the IRB.
IRB Modification Process
Need to make changes to your study protocol? Request a modification first!
The preferred method for a modification request is:
- Submit a memo detailing your proposed changes and the corresponding locations in the application and associated documents.
- Submit your application and associated documents with changes highlighted in some way (the same changes you described in the memo).
- Submit your consent documents, even if there were no changes to them.
These documents and changes will then be reviewed in the same manner as a new application (including a verification of CITI training of key personnel). If revisions are necessary, the process will proceed in the same manner as the application review process.